Article
Further evidence for a possible association between serotonin transporter gene and lithium prophylaxis in mood disorders.
The pharmacogenomics journal - 1 Jan 2004
Serretti A, Malitas P N, Mandelli L, Lorenzi C, Ploia C, Alevizos B, Nikolaou C, Boufidou F, Christodoulou G N, Smeraldi E
Abstract excerpt
We previously reported an association between the functional polymorphism in the upstream regulatory region of the serotonin transporter gene (SERTPR) and the prophylactic efficacy of lithium in a sample of 201 Italian subjects affected by Mood disorders. The aim of the present study was to replicate analyses on an independent sample. In total, 83 subjects affected by Bipolar disorder were recruited in the Mood...
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