Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Tryptophan hydroxylase gene and response to lithium prophylaxis in mood disorders.

Journal of psychiatric research - 1 Jan 2000

Serretti A, Lilli R, Lorenzi C, Gasperini M, Smeraldi E

Abstract excerpt

Lithium is an effective prophylactic agent in mood disorders but not all patients with mood disorders respond to lithium therapy; it is therefore necessary to identify responders prior to treatment. Clinical predictors account for about half of the variance and it is probable that genetic factors play a substantial role. The aim of this study was to investigate the possible association between the tryptophan...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antimanic Agents
Share to Bipolar Disorder
Share to Depressive Disorder, Major

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Follow-Up Studies

Share to Polymerase Chain Reaction

Share to Recurrence

Share to Treatment Outcome

Share to Tryptophan Hydroxylase

Source

Identifiers

PMID: 10504005
DOI: 10.1016/s0022-3956(99)00013-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Tryptophan hydroxylase gene and response to lithium prophylaxis in mood disorders.PMID 10504005Read ↗

Serotonin transporter gene associated with lithium prophylaxis in mood disorders.Semantic proximity Read ↗

Serotonin receptor 2A, 2C, 1A genes and response to lithium prophylaxis in mood disorders.Semantic proximity Read ↗

Association between the tryptophan hydroxylase gene and manic-depressive illness.Semantic proximity Read ↗

Influence of 5-HTTLPR and TPH variants on illness time course in mood disorders.Semantic proximity Read ↗

Further evidence for a possible association between serotonin transporter gene and lithium prophylaxis in mood disorders.Semantic proximity Read ↗

Pharmacogenetics in affective disorders.Semantic proximity Read ↗

Tryptophan hydroxylase gene polymorphism (A218C) and suicidal behaviors.Semantic proximity Read ↗

The tryptophan hydroxylase gene influences risk for bipolar disorder but not major depressive disorder: results of meta-analyses.Semantic proximity Read ↗

TPH2 polymorphisms may modify clinical picture in treatment-resistant depression.Semantic proximity Read ↗

Association between single nucleotide polymorphisms of TPH1 and TPH2 genes, and depressive disorders.Semantic proximity Read ↗

Lithium long-term treatment in mood disorders: clinical and genetic predictors.Semantic proximity Read ↗

Prophylactic effect of lithium in bipolar affective illness may be related to serotonin transporter genotype.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.