Article
Prophylactic effect of lithium in bipolar affective illness may be related to serotonin transporter genotype.
Pharmacological reports : PR - 1 Jan 2000
Rybakowski Janusz K, Suwalska Aleksandra, Czerski Piotr M, Dmitrzak-Weglarz Monika, Leszczynska-Rodziewicz Anna, Hauser Joanna
Abstract excerpt
Serotonin transporter promoter length polymorphism (5-HTTLPR) has been implicated in the pathogenesis of mood disorders and in the therapeutic response to serotonergic drugs. In this study, the 5-HTTLPR was estimated in 67 patients with bipolar mood disorder, receiving lithium carbonate for prophylactic purposes for the period of more than 5 years (mean 15 years). The patients were divided into excellent...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
