Article
Serotonin transporter gene associated with lithium prophylaxis in mood disorders.
The pharmacogenomics journal - 1 Jan 2001
Serretti A, Lilli R, Mandelli L, Lorenzi C, Smeraldi E
Abstract excerpt
The aim of this study was to investigate the possible association between the functional polymorphism in the upstream regulatory region of the serotonin transporter gene (5-HTTLPR) and the prophylactic efficacy of lithium in mood disorders. Two hundred and one subjects affected by bipolar (n = 167) and major depressive (n = 34) disorder were followed prospectively for an average of 58.2 months and were typed for...
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