Article
Response to lithium prophylaxis: interaction between serotonin transporter and BDNF genes.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Sept 2007
Rybakowski Janusz K, Suwalska Aleksandra, Skibinska Maria, Dmitrzak-Weglarz Monika, Leszczynska-Rodziewicz Anna, Hauser Joanna
Abstract excerpt
Both serotonin transporter and brain-derived neurotrophic factor (BDNF) genes have been previously implicated in the efficacy of lithium prophylaxis. The aim of the present study was to assess a possible interaction between serotonin transporter genotype (5HTTLPR) and BDNF Val66Met polymorphism, and the prophylactic response to lithium. The study was performed on 111 patients with bipolar mood disorders (43 male,...
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