Article
Telomere length homeostasis is achieved via a switch between telomerase- extendible and -nonextendible states.
Cell - 30 Apr 2004
Teixeira M Teresa, Arneric Milica, Sperisen Peter, Lingner Joachim
Abstract excerpt
Telomerase counteracts telomere erosion that stems from incomplete chromosome end replication and nucleolytic processing. A precise understanding of telomere length homeostasis has been hampered by the lack of assays that delineate the nonuniform telomere extension events of single chromosome molecules. Here, we measure telomere elongation at nucleotide resolution in Saccharomyces cerevisiae. The number of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
