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Article

Natural diversity of telomere length distributions across 100 Saccharomyces cerevisiae strains.

Genome research - 2 Mar 2026

Garrido Clotilde, Gómez-Muñoz Cintia, Kornobis Etienne, Agier Nicolas, Ilioaia Oana, Fischer Gilles, Xu Zhou

Abstract excerpt

Telomeres gradually shorten at each cell division, and telomerase counteracts this shortening by elongating telomere sequences. This dynamic balance between elongation and shortening results in a steady-state telomere length (TL) distribution. Here, we develop a method for detecting telomeric sequences in Saccharomyces cerevisiae genomes from raw Oxford Nanopore Technologies (ONT) sequencing reads, providing a...

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Identifiers

PMID: 41545084
DOI: 10.1101/gr.281132.125
PMCID: PMC12951964

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