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Article

The initiative role of XPC protein in cisplatin DNA damaging treatment-mediated cell cycle regulation

19 Apr 2004

Abstract excerpt

XPC is an important DNA damage recognition protein involved in DNA nucleotide excision repair. We have studied the role of the XPC protein in cisplatin treatment-mediated cell cycle regulation. Through the comparison of microarray data obtained from human normal fibroblasts and two individual XPC-defective cell lines, 486 genes were identified as XPC-responsive genes in the cisplatin treatment (with a minimal...

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PMID: 15107491
DOI: 10.1093/nar/gkh541

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Source receipt: pubmed, retrieved 7 Sept 2026.

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