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Article

Attenuated expression of xeroderma pigmentosum group C is associated with critical events in human bladder cancer carcinogenesis and progression.

Cancer research - 15 May 2007

Chen Zhiwen, Yang Jin, Wang Gan, Song Bo, Li Jin, Xu Zhigang

Abstract excerpt

Xeroderma pigmentosum group C (XPC) is an important DNA damage recognition protein that binds to damaged DNA at a very early stage during DNA repair. The XPC protein is also involved in DNA damage-induced cell cycle checkpoint regulation and apoptosis. XPC defects are associated with many types of solid tumors. The mechanism of the XPC protein in cancer progression, however, remains unclear. In this report, we...

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Source

Identifiers

PMID: 17510383
DOI: 10.1158/0008-5472.CAN-06-0877

Genes

XPC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Attenuated expression of xeroderma pigmentosum group C is associated with critical events in human bladder cancer carcinogenesis and progression.PMID 17510383Read ↗

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Response of the Urothelial Carcinoma Cell Lines to CisplatinSemantic proximity Read ↗

p53 and DNA damage-inducible expression of the xeroderma pigmentosum group C geneSemantic proximity Read ↗

Mouse models for xeroderma pigmentosum group A and group C show divergent cancer phenotypes.Semantic proximity Read ↗

Xeroderma Pigmentosum C (XPC) Mutations in Primary Fibroblasts Impair Base Excision Repair Pathway and Increase Oxidative DNA DamageSemantic proximity Read ↗

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Novel mutation identified in the DDB2 gene in patients with xeroderma pigmentosum group-E.Semantic proximity Read ↗

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