Article
Transforming growth factor-beta1 polymorphisms in Korean patients with systemic sclerosis.
Tissue antigens - 1 May 2004
Lee E B, Kim J Y, Lee Y J, Abdallah A, Lympany P, Song Y W
Abstract excerpt
Transforming growth factor-beta1 (TGF-beta1) plays an important role in the pathogenesis of systemic sclerosis (SSc). To investigate the role of TGF-beta1 gene polymorphisms in SSc, we genotyped six biallelic polymorphic positions (position -988, -800, and -509; and codons 10, 25, and 263) in 61 Korean SSc patients and in 148 healthy controls, using polymerase chain reaction-sequence-specific primers. Genetic...
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