Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genotypic analysis of the TGF beta-509 allele in patients with systemic lupus erythematosus and Sjogren's syndrome.

Annales de genetique - 1 Jan 2000

Caserta Tina M, Knisley Alyssa A, Tan Filemon K, Arnett Frank C, Brown Thomas L

Abstract excerpt

Transforming growth factor beta (TGFbeta) is a secreted protein present in the circulation and is a critical regulator of the body's immune system. TGFbeta is believed to control several components of the immune system and inhibit autoimmune reactions. Systemic lupus erythematosus (SLE) and Sjogren's syndrome (SS) are prototypical human autoimmune diseases characterized by the circulating autoantibodies directed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA
Share to Gene Frequency
Share to Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lupus Erythematosus, Systemic

Share to Polymerase Chain Reaction

Share to Polymorphism, Restriction Fragment Length

Share to Sjogren's Syndrome

Share to Transforming Growth Factor beta

Source

Identifiers

PMID: 15581833
DOI: 10.1016/j.anngen.2004.07.003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genotypic analysis of the TGF beta-509 allele in patients with systemic lupus erythematosus and Sjogren's syndrome.PMID 15581833Read ↗

The transforming growth factor-beta1 gene polymorphism (G915C) is not associated with systemic lupus erythematosus.Semantic proximity Read ↗

Single-nucleotide polymorphisms of transforming growth factor-beta1 gene in Taiwanese patients with systemic lupus erythematosus.Semantic proximity Read ↗

The association between C509T, T869C, G915C gene polymorphisms of transforming growth factor-β1 and systemic lupus erythematosus risk: A meta-analysis.Semantic proximity Read ↗

TGFB1 +869 T > C (rs1800470) variant is independently associated with susceptibility, laboratory activity, and TGF-β1 in patients with systemic lupus erythematosus.Semantic proximity Read ↗

Single nucleotide polymorphism T869C of transforming growth factor-beta 1 gene and systemic lupus erythematosus: association with disease susceptibility and lupus nephritis.Semantic proximity Read ↗

Transforming growth factor-beta1 polymorphisms in Korean patients with systemic sclerosis.Semantic proximity Read ↗

Analysis of transforming growth factor beta1 gene polymorphisms in patients with systemic sclerosis.Semantic proximity Read ↗

Association between circulating transforming growth factor-β1 level and polymorphisms in systemic lupus erythematosus and rheumatoid arthritis: A meta-analysis.Semantic proximity Read ↗

Genetic control of the circulating concentration of transforming growth factor type beta1.Semantic proximity Read ↗

A polymorphism in the CTGF promoter region associated with systemic sclerosis.Semantic proximity Read ↗

C-509T polymorphism in the TGFB1 gene promoter: impact on Crohn's disease susceptibility and clinical course?Semantic proximity Read ↗

Association of C-509T and T869C polymorphisms of transforming growth factor-beta1 gene with susceptibility to and progression of IgA nephropathy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.