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Article

Interleukin-10 gene promoter and NFKB1 promoter insertion/deletion polymorphisms in systemic sclerosis.

Scandinavian journal of immunology - 1 Feb 2013

Salim P H, Jobim M, Bredemeier M, Chies J A B, Brenol J C T, Jobim L F, Xavier R M

Abstract excerpt

Systemic sclerosis (SSc) is a connective tissue disease characterized by fibrotic, immunological and vascular abnormalities. Nuclear factor-kB (NFKB), as a key transcription factor involved in the regulation of immune responses, appears to be a good candidate for studies on the pathogenesis of autoimmune diseases, as well as the interleukin-10 (IL-10) polymorphism, which other studies have suggested an...

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Source

Identifiers

PMID: 23237063
DOI: 10.1111/sji.12020

Genes

NFKB1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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