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Article

Conserved but nonessential interaction of SRP RNA with translation factor EF-G.

RNA (New York, N.Y.) - 1 May 2004

Sagar Madi Bidya, Lucast Louise, Doudna Jennifer A

Abstract excerpt

4.5S RNA is essential for viability of Escherichia coli, and forms a key component of the signal recognition particle (SRP), a ubiquitous ribonucleoprotein complex responsible for cotranslational targeting of secretory proteins. 4.5S RNA also binds independently to elongation factor G (EF-G), a five-domain GTPase that catalyzes the translocation step during protein biosynthesis on the ribosome. Point mutations in...

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Identifiers

PMID: 15100432
DOI: 10.1261/rna.5266504
PMCID: PMC1370567

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Conserved but nonessential interaction of SRP RNA with translation factor EF-G.PMID 15100432Read ↗

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