Article
An E. coli ribonucleoprotein containing 4.5S RNA resembles mammalian signal recognition particle.
Science (New York, N.Y.) - 23 Nov 1990
Poritz M A, Bernstein H D, Strub K, Zopf D, Wilhelm H, Walter P
Abstract excerpt
The signal recognition particle (SRP) plays a central role in directing the export of nascent proteins from the cytoplasm of mammalian cells. An SRP-dependent translocation machinery in bacteria has not been demonstrated in previous genetic and biochemical studies. Sequence comparisons, however,...
Topics
- Bacterial Proteins
- Base Sequence
- Enzyme Activation
- Escherichia coli
- GTP Phosphohydrolases
- Genes, Bacterial
- Heat-Shock Proteins
- Hot Temperature
- Immunosorbent Techniques
- Isopropyl Thiogalactoside
- Molecular Sequence Data
- Mutation
- Protein Sorting Signals
- RNA, Bacterial
- Recombinant Fusion Proteins
- Ribonucleoproteins
- Sequence Homology, Nucleic Acid
- Signal Recognition Particle