Evolutionary conserved nucleotides within the E.coli 4.5S RNA are required for association with P48 in vitro and for optimal function in vivo.

doi:10.1093/nar/20.22.5919

Article

Evolutionary conserved nucleotides within the E.coli 4.5S RNA are required for association with P48 in vitro and for optimal function in vivo.

Nucleic acids research - 25 Nov 1992

Wood H, Luirink J, Tollervey D

Abstract excerpt

E.coli 4.5S RNA is homologous to domain IV of eukaryotic SPR7S RNA, the RNA component of the signal recognition particle. The 4.5S RNA is associated in vivo with a 48kD protein (P48), which is homologous to a protein component of the signal recognition particle, SRP54. In addition to secondary st...

Topics

Alleles
Base Sequence
Biological Evolution
Conserved Sequence
Escherichia coli
Molecular Sequence Data
Mutagenesis, Site-Directed
Nucleic Acid Conformation
Plasmids
Protein Binding
RNA, Bacterial
RNA, Ribosomal
Ribonucleoproteins
Signal Recognition Particle

Evolutionary conserved nucleotides within the E.coli 4.5S RNA are required for association with P48 in vitro and for optimal function in vivo.

Abstract excerpt

Topics

Discuss the evidence