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Article

Functional analysis of the signal recognition particle in Escherichia coli by characterization of a temperature-sensitive ffh mutant.

Journal of bacteriology - 1 May 2002

Park Sei-Kyoung, Jiang Fenglei, Dalbey Ross E, Phillips Gregory J

Abstract excerpt

The Ffh protein of Escherichia coli is a 48-kDa polypeptide that is homologous to the SRP54 subunit of the eukaryotic signal recognition particle (SRP). Efforts to understand the function of Ffh in bacteria have depended largely on the use of E. coli strains that allow depletion of the wild-type gene product. As an alternative approach to studying Ffh, a temperature-sensitive ffh mutant was isolated. The...

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Identifiers

PMID: 11976293
DOI: 10.1128/JB.184.10.2642-2653.2002
PMCID: PMC135024

Genes

SRP54

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Functional analysis of the signal recognition particle in Escherichia coli by characterization of a temperature-sensitive ffh mutant.PMID 11976293Read ↗

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