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Article

The signal recognition particle (SRP) RNA links conformational changes in the SRP to protein targeting.

Molecular biology of the cell - 1 Jul 2007

Bradshaw Niels, Walter Peter

Abstract excerpt

The RNA component of the signal recognition particle (SRP) is universally required for cotranslational protein targeting. Biochemical studies have shown that SRP RNA participates in the central step of protein targeting by catalyzing the interaction of the SRP with the SRP receptor (SR). SRP RNA also accelerates GTP hydrolysis in the SRP.SR complex once formed. Using a reverse-genetic and biochemical analysis, we...

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Identifiers

PMID: 17507650
DOI: 10.1091/mbc.e07-02-0117
PMCID: PMC1924838

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The signal recognition particle (SRP) RNA links conformational changes in the SRP to protein targeting.PMID 17507650Read ↗

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