Article
Gene-specific modulation of TAF10 function by SET9-mediated methylation.
Molecular cell - 23 Apr 2004
Kouskouti Antigone, Scheer Elisabeth, Staub Adrien, Tora Làszlò, Talianidis Iannis
Abstract excerpt
SET9 is a member of the SET domain-containing histone methyltransferase family that can specifically methylate histone 3 at lysine 4 position. Although nucleosomal histones are poor substrates for SET9, the active enzyme can stimulate activator-induced transcription. Here, we show that SET9 can m...
Topics
- Amino Acid Sequence
- Antibodies, Monoclonal
- Baculoviridae
- Binding Sites
- Cell Line
- Cell Nucleus
- Escherichia coli
- Gene Expression Regulation
- Genes, Reporter
- Genetic Vectors
- HeLa Cells
- Histones
- Humans
- Lysine
- Methylation
- Methyltransferases
- Mutation
- Nucleosomes