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Article

A motif within SET-domain proteins binds single-stranded nucleic acids and transcribed and supercoiled DNAs and can interfere with assembly of nucleosomes.

Molecular and cellular biology - 1 Mar 2005

Krajewski Wladyslaw A, Nakamura Tatsuya, Mazo Alexander, Canaani Eli

Abstract excerpt

The evolutionary conserved SET domain is present in many eukaryotic chromatin-associated proteins, including some members of the trithorax (TrxG) group and the polycomb (PcG) group of epigenetic transcriptional regulators and modifiers of position effect variegation. All SET domains examined exhibited histone lysine methyltransferase activity, implicating these proteins in the generation of epigenetic marks....

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Identifiers

PMID: 15713643
DOI: 10.1128/MCB.25.5.1891-1899.2005
PMCID: PMC549386

Genes

SET

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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