Article
An essential interaction between T-box proteins and histone-modifying enzymes.
Epigenetics - 16 Feb 2009
Miller Sara A, Weinmann Amy S
Abstract excerpt
Cellular differentiation requires precisely coordinated events to induce developmentally appropriate gene expression profiles. Lineage-defining transcription factors are responsible for establishing cell-type specific gene expression patterns during development. Recently, we reported a novel mechanism by which the T-box transcription factor T-bet interacts with JMJD3, an H3K27-demethylase, and Set7/9, an...
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