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Article

Functional stoichiometry and local enrichment of calmodulin interacting with Ca2+ channels.

Science (New York, N.Y.) - 16 Apr 2004

Mori Masayuki X, Erickson Michael G, Yue David T

Abstract excerpt

Calmodulin (CaM) interactions with Ca2+ channels mediate both Ca2+ regulation of channels and local Ca2+ triggering of transcription factors implicated in neuronal memory. Crucial to these functions are the number of CaM molecules (CaMs) regulating each channel, and the number of CaMs privy to the local Ca2+ signal from each channel. To resolve these parameters, we fused L-type Ca2+ channels to single CaM...

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Identifiers

PMID: 15087548
DOI: 10.1126/science.1093490

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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