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Article

Signaling to the nucleus by an L-type calcium channel-calmodulin complex through the MAP kinase pathway.

Science (New York, N.Y.) - 12 Oct 2001

Dolmetsch R E, Pajvani U, Fife K, Spotts J M, Greenberg M E

Abstract excerpt

Increases in the intracellular concentration of calcium ([Ca2+]i) activate various signaling pathways that lead to the expression of genes that are essential for dendritic development, neuronal survival, and synaptic plasticity. The mode of Ca2+ entry into a neuron plays a key role in determining which signaling pathways are activated and thus specifies the cellular response to Ca2+. Ca2+ influx through L-type...

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Identifiers

PMID: 11598293
DOI: 10.1126/science.1063395

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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