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Article

Calmodulin is the Ca2+ sensor for Ca2+ -dependent inactivation of L-type calcium channels.

Neuron - 1 Mar 1999

Peterson B Z, DeMaria C D, Adelman J P, Yue D T

Abstract excerpt

Elevated intracellular Ca2+ triggers inactivation of L-type calcium channels, providing negative Ca2+ feedback in many cells. Ca2+ binding to the main alpha1c channel subunit has been widely proposed to initiate such Ca2+ -dependent inactivation. Here, we find that overexpression of mutant, Ca2+...

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Source

Identifiers

PMID: 10197534
DOI: 10.1016/s0896-6273(00)80709-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-10197534-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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