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Article

Nrf2 deficiency improves autoimmune nephritis caused by the fas mutation lpr.

Kidney international - 1 May 2004

Morito Naoki, Yoh Keigyou, Hirayama Aki, Itoh Ken, Nose Masato, Koyama Akio, Yamamoto Masayuki, Takahashi Satoru

Abstract excerpt

BACKGROUND: Nrf2 is a basic leucine zipper transcriptional activator essential for the coordinate transcriptional induction of antioxidant and phase II drug metabolizing enzymes. We previously reported that Nrf2-deficient female mice develop lupus-like autoimmune nephritis (Kidney Int 60:1343-135...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15086909
DOI: 10.1111/j.1523-1755.2004.00565.x

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15086909-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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