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Article

Human centromere repositioning "in progress".

Proceedings of the National Academy of Sciences of the United States of America - 27 Apr 2004

Amor David J, Bentley Karen, Ryan Jacinta, Perry Jo, Wong Lee, Slater Howard, Choo K H Andy

Abstract excerpt

Centromere repositioning provides a potentially powerful evolutionary force for reproductive isolation and speciation, but the underlying mechanisms remain ill-defined. An attractive model is through the simultaneous inactivation of a normal centromere and the formation of a new centromere at a hitherto noncentromeric chromosomal location with minimal detrimental effect. We report a two-generation family in which...

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Source

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Identifiers

PMID: 15084747
DOI: 10.1073/pnas.0308637101
PMCID: PMC404081

Genes

BUB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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