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Article

Intercellular signaling of reproductive development by the C. elegans DAF-9 cytochrome P450.

Development (Cambridge, England) - 1 Apr 2004

Mak Ho Yi, Ruvkun Gary

Abstract excerpt

Parallel pathways control C. elegans reproductive development in response to environmental cues. Attenuation of daf-2 insulin-like or daf-7 TGFbeta-like signaling pathways cause developmental arrest at the stress resistant and long-lived dauer stage. Loss-of-function mutations in the cytochrome P450 gene daf-9 also cause dauer arrest and defects in cell migration. A rescuing daf-9::GFP fusion gene driven by the...

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PMID: 15084462
DOI: 10.1242/dev.01069

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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