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Article

Caenorhabditis elegans SDF-9 enhances insulin/insulin-like signaling through interaction with DAF-2.

Genetics - 1 Sept 2007

Jensen Victor L, Albert Patrice S, Riddle Donald L

Abstract excerpt

SDF-9 is a modulator of Caenorhabditis elegans insulin/IGF-1 signaling that may interact directly with the DAF-2 receptor. SDF-9 is a tyrosine phosphatase-like protein that, when mutated, enhances many partial loss-of-function mutants in the dauer pathway except for the temperature-sensitive mutant daf-2(m41). We propose that SDF-9 stabilizes the active phosphorylated state of DAF-2 or acts as an adaptor protein...

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Identifiers

PMID: 17660545
DOI: 10.1534/genetics.107.076703
PMCID: PMC2013707

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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