Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

daf-12 regulates developmental age and the dauer alternative in Caenorhabditis elegans.

Development (Cambridge, England) - 1 Apr 1998

Antebi A, Culotti J G, Hedgecock E M

Abstract excerpt

From egg through adult, C. elegans has six life stages including an option for dauer formation and diapause at larval stage L3 in adverse environments. Somatic cells throughout the organism make consistent choices and advance in unison, suggesting a mechanism of coordinate regulation at these stage transitions. Earlier studies showed that daf-12, which encodes a nuclear receptor (W. Yeh, 1991, Doctoral Thesis....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Chromosome Mapping
Share to Gene Expression Regulation, Developmental

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mutagenesis

Share to Phenotype

Share to Signal Transduction

Share to Temperature

Share to X Chromosome

Source

Identifiers

PMID: 9477318
DOI: 10.1242/dev.125.7.1191

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

daf-12 regulates developmental age and the dauer alternative in Caenorhabditis elegans.PMID 9477318Read ↗

daf-12 encodes a nuclear receptor that regulates the dauer diapause and developmental age in C. elegans.Semantic proximity Read ↗

A feedback circuit involving let-7-family miRNAs and DAF-12 integrates environmental signals and developmental timing in Caenorhabditis elegans.Semantic proximity Read ↗

Structure and expression of daf-12: a nuclear hormone receptor with three isoforms that are involved in development and aging in Caenorhabditis elegans.Semantic proximity Read ↗

Two pleiotropic classes of daf-2 mutation affect larval arrest, adult behavior, reproduction and longevity in Caenorhabditis elegans.Semantic proximity Read ↗

Genetic analysis of the roles of daf-28 and age-1 in regulating Caenorhabditis elegans dauer formation.Semantic proximity Read ↗

The nuclear hormone receptor DAF-12 has opposing effects on Caenorhabditis elegans lifespan and regulates genes repressed in multiple long-lived worms.Semantic proximity Read ↗

Control of Caenorhabditis elegans life history by nuclear receptor signal transduction.Semantic proximity Read ↗

A novel nuclear receptor/coregulator complex controls C. elegans lipid metabolism, larval development, and aging.Semantic proximity Read ↗

Genes that regulate both development and longevity in Caenorhabditis elegans.Semantic proximity Read ↗

DAF-12 germline-to-soma signaling mediates transgenerational longevity in <i>C. elegans</i>Semantic proximity Read ↗

Cell nonautonomy of C. elegans daf-2 function in the regulation of diapause and life span.Semantic proximity Read ↗

daf-2, daf-16 and daf-23: genetically interacting genes controlling Dauer formation in Caenorhabditis elegans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.