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Article

The terminal differentiation factor LIN-29 is required for proper vulval morphogenesis and egg laying in Caenorhabditis elegans.

Development (Cambridge, England) - 1 Nov 1997

Bettinger J C, Euling S, Rougvie A E

Abstract excerpt

Caenorhabditis elegans vulval development culminates during exit from the L4-to-adult molt with the formation of an opening through the adult hypodermis and cuticle that is used for egg laying and mating. Vulva formation requires the heterochronic gene lin-29, which triggers hypodermal cell termi...

Topics

Animals
Caenorhabditis elegans
Caenorhabditis elegans Proteins
Cell Differentiation
Cell Fusion
Codon, Terminator
DNA-Binding Proteins
Female
Larva
Mosaicism
Mutation
Oviposition

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

Transcription Factors

Uterus

Vulva

Source

Identifiers

PMID: 9334281
DOI: 10.1242/dev.124.21.4333

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9334281-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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The terminal differentiation factor LIN-29 is required for proper vulval morphogenesis and egg laying in Caenorhabditis elegans.PMID 9334281Read ↗

The Caenorhabditis elegans heterochronic gene lin-29 coordinates the vulval-uterine-epidermal connections.Semantic proximity Read ↗

The LIN-29 transcription factor is required for proper morphogenesis of the Caenorhabditis elegans male tail.Semantic proximity Read ↗

The Caenorhabditis elegans heterochronic gene lin-14 coordinates temporal progression and maturation in the egg-laying system.Semantic proximity Read ↗

The Caenorhabditis elegans EGL-26 protein mediates vulval cell morphogenesis.Semantic proximity Read ↗

Isolation and characterization of mutations causing abnormal eversion of the vulva in Caenorhabditis elegans.Semantic proximity Read ↗

Limitation of the size of the vulval primordium of Caenorhabditis elegans by lin-15 expression in surrounding hypodermis.Semantic proximity Read ↗

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Heterochronic genes control cell cycle progress and developmental competence of C. elegans vulva precursor cells.Semantic proximity Read ↗

Necessity and Contingency in Developmental Genetic Screens: EGF, Wnt, and Semaphorin Pathways in Vulval Induction of the Nematode Oscheius tipulae.Semantic proximity Read ↗

A deficiency screen for zygotic loci required for establishment and patterning of the epidermis in Caenorhabditis elegans.Semantic proximity Read ↗

Cell fates and fusion in the C. elegans vulval primordium are regulated by the EGL-18 and ELT-6 GATA factors -- apparent direct targets of the LIN-39 Hox protein.Semantic proximity Read ↗

Protruding vulva mutants identify novel loci and Wnt signaling factors that function during Caenorhabditis elegans vulva development.Semantic proximity Read ↗

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