Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification and functional characterization of the natural variant MRP3-Arg1297His of human multidrug resistance protein 3 (MRP3/ABCC3)

19 Mar 2004

Abstract excerpt

The human multidrug resistance protein 3 (MRP3, symbol ABCC3) is an ATP-binding cassette transporter that mediates the efflux of organic anions, including lipophilic substances conjugated with glucuronate, sulphate or glutathione, across the basolateral membrane of polarized cells (e.g. hepatocytes) into blood. Genetic variants of MRP3 may affect the transport of these substances out of cells. The aims of this...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drug Transport and Resistance Mechanisms
Share to Hemoglobinopathies and Related Disorders
Share to Neonatal Health and Biochemistry

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15083066
DOI: 10.1097/00008571-200404000-00001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification and functional characterization of the natural variant MRP3-Arg1297His of human multidrug resistance protein 3 (MRP3/ABCC3)PMID 15083066Read ↗

Systematic screening of human ABCC3 polymorphisms and their effects on MRP3 expression and function.Semantic proximity Read ↗

Genetic polymorphisms in the multidrug resistance-associated protein 3 (ABCC3, MRP3) gene and relationship to its mRNA and protein expression in human liver.Semantic proximity Read ↗

Functional analysis of nonsynonymous single nucleotide polymorphism type ATP-binding cassette transmembrane transporter subfamily C member 3.Semantic proximity Read ↗

Genetic variations of the ABC transporter gene ABCC3 in a Japanese population.Semantic proximity Read ↗

Could polymorphisms in ATP-binding cassette C3/multidrug resistance associated protein 3 (ABCC3/MRP3) modify colorectal cancer risk?Semantic proximity Read ↗

Polymorphisms of the drug transporters ABCB1, ABCG2, ABCC2 and ABCC3 and their impact on drug bioavailability and clinical relevance.Semantic proximity Read ↗

Identification of human multidrug resistance protein 1 (MRP1) mutations and characterization of a G671V substitution.Semantic proximity Read ↗

Polymorphisms of MRP1 (ABCC1) and related ATP-dependent drug transportersSemantic proximity Read ↗

Substrates and Inhibitors of Human Multidrug Resistance Associated Proteins and the Implications in Drug DevelopmentSemantic proximity Read ↗

Mutations in the SLCO1B3 gene affecting the substrate specificity of the hepatocellular uptake transporter OATP1B3 (OATP8).Semantic proximity Read ↗

Functional characterization of non-synonymous single nucleotide polymorphisms in the gene encoding human multidrug resistance protein 1 (MRP1/ABCC1).Semantic proximity Read ↗

The human multidrug resistance protein 4 (MRP4, ABCC4): functional analysis of a highly polymorphic gene.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.