Article
Functional analysis of nonsynonymous single nucleotide polymorphism type ATP-binding cassette transmembrane transporter subfamily C member 3.
Pharmacogenetics and genomics - 1 Sept 2008
Kobayashi Kazuhiro, Ito Kousei, Takada Tappei, Sugiyama Yuichi, Suzuki Hiroshi
Abstract excerpt
OBJECTIVES: The multidrug resistance-associated protein 3/ATP-binding cassette transmembrane transporter subfamily C member 3 (MRP3/ABCC3) plays an important role in exporting endogenous and xenobiotic anionic substrates, including glucuronide conjugates of xenobiotics, from hepatocytes into the...
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