Article
Behavioral characterization of alcohol-tolerant and alcohol-nontolerant rat lines and an f(2) generation.
Behavior genetics - 1 Jul 2004
Radcliffe Richard A, Hoffmann Sarah E, Deng Xin-Sheng, Asperi William, Fay Tina, Bludeau Pequita, Erwin V Gene, Deitrich Richard A
Abstract excerpt
The Alcohol Tolerant (AT) and Alcohol Nontolerant (ANT) rats, selectively bred for ethanol-induced ataxia on the inclined plane at ALKO in Finland, were moved to the University of Colorado in 1998. The selection phenotype was tested on generation 60 animals in Colorado. In week one, ataxia was measured on the inclined plane 30 minutes after an intraperitoneal dose of 2 g/kg 15% w/v ethanol. Differences in...
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