Article
A major QTL for acute ethanol sensitivity in the alcohol tolerant and non-tolerant selected rat lines.
Genes, brain, and behavior - 1 Aug 2009
Radcliffe R A, Erwin V G, Bludeau P, Deng X, Fay T, Floyd K L, Deitrich R A
Abstract excerpt
The Alcohol Tolerant and Alcohol Non-Tolerant rats (AT, ANT) were selectively bred for ethanol-induced ataxia as measured on the inclined plane. Here we report on a quantitative trait locus (QTL) study in an F(2) intercross population derived from inbred AT and ANT (IAT, IANT) and a follow-up study of congenics that were bred to examine one of the mapped QTLs. Over 1200 F(2) offspring were tested for inclined...
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