Article
Large genetic analysis of alcohol resistance and tolerance reveals an inverse correlation and suggests ‘true’ tolerance mutants
2023-10-10
Abstract excerpt
Tolerance occurs when, following an initial experience with a substance, more of the substance is required subsequently to induce the same behavioral effects. Tolerance is historically not well-understood, and numerous researchers have turned to model organisms, particularly Drosophila melanogaster , to unravel its mechanisms. Flies have high translational relevance for human alcohol responses, and there is subst...
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Identifiers and source
- Literature Corpus work
- 2c4acd29-d0b2-597b-b7cb-3e39baea5052
- DOI
- 10.1101/2023.10.09.561599