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Article

Mouse FGF15 is the ortholog of human and chick FGF19, but is not uniquely required for otic induction.

Developmental biology - 1 May 2004

Wright Tracy J, Ladher Raj, McWhirter John, Murre Cornelis, Schoenwolf Gary C, Mansour Suzanne L

Abstract excerpt

The inner ear develops from an ectodermal placode that is specified by inductive signals from the adjacent neurectoderm and underlying mesoderm. In chick, fibroblast growth factor (Fgf)-19 is expressed in mesoderm underlying the presumptive otic placode, and human FGF19 induces expression of otic markers in a tissue explant containing neural plate and surface ectoderm. We show here that mouse Fgf15 is the...

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Source

Identifiers

PMID: 15081372
DOI: 10.1016/j.ydbio.2004.02.003

Genes

FGF19

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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