Article
Mapping of Wnt, frizzled, and Wnt inhibitor gene expression domains in the avian otic primordium
17 Jul 2009
Abstract excerpt
Wnt signaling activates at least three different pathways involved in development and disease. Interactions of secreted ligands and inhibitors with cell-surface receptors result in the activation or regulation of particular downstream intracellular cascades. During the developmental stages of otic vesicle closure and beginning morphogenesis, the forming inner ear transcribes a plethora of Wnt-related genes. We...
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