Article
Fgf3 and Fgf10 are required for mouse otic placode induction.
Development (Cambridge, England) - 1 Aug 2003
Wright Tracy J, Mansour Suzanne L
Abstract excerpt
The inner ear, which contains the sensory organs specialised for audition and balance, develops from an ectodermal placode adjacent to the developing hindbrain. Tissue grafting and recombination experiments suggest that placodal development is directed by signals arising from the underlying mesoderm and adjacent neurectoderm. In mice, Fgf3 is expressed in the neurectoderm prior to and concomitant with placode...
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