Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Fgf3 and Fgf10 are required for mouse otic placode induction.

Development (Cambridge, England) - 1 Aug 2003

Wright Tracy J, Mansour Suzanne L

Abstract excerpt

The inner ear, which contains the sensory organs specialised for audition and balance, develops from an ectodermal placode adjacent to the developing hindbrain. Tissue grafting and recombination experiments suggest that placodal development is directed by signals arising from the underlying mesod...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ear
Share to Embryonic Induction
Share to Fibroblast Growth Factor 10

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fibroblast Growth Factor 3

Share to Fibroblast Growth Factors

Share to Mesoderm

Share to Receptor, Fibroblast Growth Factor, Type 1

Share to Receptors, Fibroblast Growth Factor

Source

Identifiers

PMID: 12810586
DOI: 10.1242/dev.00555

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-12810586-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Fgf3 and Fgf10 are required for mouse otic placode induction.PMID 12810586Read ↗

Differential requirements for FGF3, FGF8 and FGF10 during inner ear development.Semantic proximity Read ↗

Gata3 is required for early morphogenesis and Fgf10 expression during otic development.Semantic proximity Read ↗

The mouse Foxi3 transcription factor is necessary for the development of posterior placodes.Semantic proximity Read ↗

Fgf3 and Fgf8 dependent and independent transcription factors are required for otic placode specification.Semantic proximity Read ↗

Fgf3 is required for dorsal patterning and morphogenesis of the inner ear epithelium.Semantic proximity Read ↗

Fgf8 and Fgf3 are required for zebrafish ear placode induction, maintenance and inner ear patterning.Semantic proximity Read ↗

FGF/FGFR-2(IIIb) signaling is essential for inner ear morphogenesis.Semantic proximity Read ↗

Analysis of mouse kreisler mutants reveals new roles of hindbrain-derived signals in the establishment of the otic neurogenic domain.Semantic proximity Read ↗

Fgf8 expression defines a morphogenetic center required for olfactory neurogenesis and nasal cavity development in the mouse.Semantic proximity Read ↗

Identification of cis-element regulating expression of the mouse Fgf10 gene during inner ear development.Semantic proximity Read ↗

Gata3 directly regulates early inner ear expression of Fgf10.Semantic proximity Read ↗

FGFs control the patterning of the inner ear but are not able to induce the full ear program.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.