Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Differential requirements for FGF3, FGF8 and FGF10 during inner ear development.

Developmental biology - 15 Aug 2007

Zelarayan Laura Cecilia, Vendrell Victor, Alvarez Yolanda, Domínguez-Frutos Elena, Theil Thomas, Alonso Maria Teresa, Maconochie Mark, Schimmang Thomas

Abstract excerpt

FGF signaling is required during multiple stages of inner ear development in many different vertebrates, where it is involved in induction of the otic placode, in formation and morphogenesis of the otic vesicle as well as for cellular differentiation within the sensory epithelia. In this study we have looked to define the redundant and conserved roles of FGF3, FGF8 and FGF10 during the development of the murine...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chick Embryo
Share to Ear, Inner

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fibroblast Growth Factor 10

Share to Fibroblast Growth Factor 3

Share to Fibroblast Growth Factor 8

Share to Gene Expression Regulation, Developmental

Share to Recombinant Proteins

Share to RNA, Small Interfering

Source

Identifiers

PMID: 17601531
DOI: 10.1016/j.ydbio.2007.05.033

Genes

FGF10
FGF3
FGF8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Differential requirements for FGF3, FGF8 and FGF10 during inner ear development.PMID 17601531Read ↗

Fgf3 and Fgf10 are required for mouse otic placode induction.Semantic proximity Read ↗

Fgf3 is required for dorsal patterning and morphogenesis of the inner ear epithelium.Semantic proximity Read ↗

Fgf8 and Fgf3 are required for zebrafish ear placode induction, maintenance and inner ear patterning.Semantic proximity Read ↗

FGF/FGFR-2(IIIb) signaling is essential for inner ear morphogenesis.Semantic proximity Read ↗

Gata3 is required for early morphogenesis and Fgf10 expression during otic development.Semantic proximity Read ↗

Fgf3 and Fgf8 dependent and independent transcription factors are required for otic placode specification.Semantic proximity Read ↗

Analysis of mouse kreisler mutants reveals new roles of hindbrain-derived signals in the establishment of the otic neurogenic domain.Semantic proximity Read ↗

Identification of cis-element regulating expression of the mouse Fgf10 gene during inner ear development.Semantic proximity Read ↗

FGFs control the patterning of the inner ear but are not able to induce the full ear program.Semantic proximity Read ↗

An expanded domain of fgf3 expression in the hindbrain of zebrafish valentino mutants results in mis-patterning of the otic vesicle.Semantic proximity Read ↗

Fgf8 expression defines a morphogenetic center required for olfactory neurogenesis and nasal cavity development in the mouse.Semantic proximity Read ↗

Gata3 directly regulates early inner ear expression of Fgf10.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.