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Article

Dynamic expression of Lgr5, a Wnt target gene, in the developing and mature mouse cochlea.

Journal of the Association for Research in Otolaryngology : JARO - 1 Aug 2011

Chai Renjie, Xia Anping, Wang Tian, Jan Taha Adnan, Hayashi Toshinori, Bermingham-McDonogh Olivia, Cheng Alan Gi-Lun

Abstract excerpt

The Wnt signaling pathway is a recurring theme in tissue development and homeostasis. Its specific roles during inner ear development are just emerging, but few studies have characterized Wnt target genes. Lgr5, a member of the G protein-coupled receptor family, is a Wnt target in the gastrointestinal and integumentary systems. Although its function is unknown, its deficiency leads to perinatal lethality due to...

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Identifiers

PMID: 21472479
DOI: 10.1007/s10162-011-0267-2
PMCID: PMC3123443

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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