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Article

Paraoxonase gene polymorphism and the risk for Alzheimer's disease in the polish population.

Dementia and geriatric cognitive disorders - 1 Jan 2011

Klimkowicz-Mrowiec A, Marona M, Wolkow P, Witkowski A, Maruszak A, Styczynska M, Barcikowska M, Szczudlik A, Slowik A

Abstract excerpt

BACKGROUND: The relationship between different paraoxonase (PON) gene polymorphisms and the risk of Alzheimer's disease (AD) was studied several times and the results were controversial. METHODS: We investigated the association of 4 single-nucleotide polymorphisms (SNPs) of the PON1 (M55L; Q192R; -161C/T) and the PON2 (C311S) genes that were shown to affect the risk of sporadic AD. We studied 360 Caucasian cases...

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Identifiers

PMID: 21757906
DOI: 10.1159/000329571

Genes

PON1
PON2

Variants

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