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Identification of quantitative trait loci that modify the severity of hereditary spherocytosis in wan, a new mouse model of band-3 deficiency.

Blood - 15 Apr 2004

Peters Luanne L, Swearingen Rebecca A, Andersen Sabra G, Gwynn Babette, Lambert Amy J, Li Renhua, Lux Samuel E, Churchill Gary A

Abstract excerpt

Defects in red blood cell (RBC) membrane skeleton components cause hereditary spherocytosis (HS). Clinically, HS varies significantly even among individuals with identical gene defects, illustrating the profound effects of genetic background on disease severity. We exploited a new spontaneous mou...

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PMID: 15070709
DOI: 10.1182/blood-2003-08-2813

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15070709-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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