Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of evolutionary hotspots in the rodent genomes.

Genome research - 1 Apr 2004

Yap Von Bing, Pachter Lior

Abstract excerpt

We describe a whole-genome comparative analysis of the human, mouse, and rat genomes to describe the average substitution patterns of four genomic regions: ancient repeats, rodent-specific DNA, exons, and conserved (coding and noncoding) regions, and to identify rodent evolutionary hotspots. In all types of regions, except the rodent-specific DNA, the rat branch is slightly longer than the mouse branch. Moreover,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Conserved Sequence
Share to Genome
Share to Genome, Human

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Repetitive Sequences, Nucleic Acid

Share to Sensitivity and Specificity

Share to Sequence Alignment

Share to Species Specificity

Source

Open in PubMed Open full text

Identifiers

PMID: 15059998
DOI: 10.1101/gr.1967904
PMCID: PMC383301

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of evolutionary hotspots in the rodent genomes.PMID 15059998Read ↗

Substantial regional variation in substitution rates in the human genome: importance of GC content, gene density, and telomere-specific effects.Semantic proximity Read ↗

Mutation hot spots in mammalian mitochondrial DNA.Semantic proximity Read ↗

Meiotic recombination strongly influences GC-content evolution in short regions in the mouse genome.Semantic proximity Read ↗

Comparative recombination rates in the rat, mouse, and human genomes.Semantic proximity Read ↗

Runaway GC Evolution in Gerbil Genomes.Semantic proximity Read ↗

Hotspots of biased nucleotide substitutions in human genes.Semantic proximity Read ↗

The evolution of lineage-specific clusters of single nucleotide substitutions in the human genome.Semantic proximity Read ↗

Covariation in frequencies of substitution, deletion, transposition, and recombination during eutherian evolution.Semantic proximity Read ↗

Characterization of evolutionary rates and constraints in three Mammalian genomes.Semantic proximity Read ↗

Patterns of insertions and their covariation with substitutions in the rat, mouse, and human genomes.Semantic proximity Read ↗

A novel method with improved power to detect recombination hotspots from polymorphism data reveals multiple hotspots in human genes.Semantic proximity Read ↗

Increased substitution rates surrounding low-complexity regions within primate proteins.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.