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Article

Mutation hot spots in mammalian mitochondrial DNA.

Genome research - 1 Feb 2006

Galtier Nicolas, Enard David, Radondy Yoan, Bazin Eric, Belkhir Khalid

Abstract excerpt

Animal mitochondrial DNA is characterized by a remarkably high level of within-species homoplasy, that is, phylogenetic incongruence between sites of the molecule. Several investigators have invoked recombination to explain it, challenging the dogma of maternal, clonal mitochondrial inheritance in animals. Alternatively, a high level of homoplasy could be explained by the existence of mutation hot spots. By using...

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Identifiers

PMID: 16354751
DOI: 10.1101/gr.4305906
PMCID: PMC1361717

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