Article
Patterns of insertions and their covariation with substitutions in the rat, mouse, and human genomes.
Genome research - 1 Apr 2004
Yang Shan, Smit Arian F, Schwartz Scott, Chiaromonte Francesca, Roskin Krishna M, Haussler David, Miller Webb, Hardison Ross C
Abstract excerpt
The rates at which human genomic DNA changes by neutral substitution and insertion of certain families of transposable elements covary in large, megabase-sized segments. We used the rat, mouse, and human genomic DNA sequences to examine these processes in more detail in comparisons over both shorter (rat-mouse) and longer (rodent-primate) times, and demonstrated the generality of the covariation. Different...
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