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Article

Increased substitution rates surrounding low-complexity regions within primate proteins.

Genome biology and evolution - 1 Mar 2014

Lenz Carolyn, Haerty Wilfried, Golding G Brian

Abstract excerpt

Previous studies have found that DNA-flanking low-complexity regions (LCRs) have an increased substitution rate. Here, the substitution rate was confirmed to increase in the vicinity of LCRs in several primate species, including humans. This effect was also found among human sequences from the 1000 Genomes Project. A strong correlation was found between average substitution rate per site and distance from the...

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Identifiers

PMID: 24572016
DOI: 10.1093/gbe/evu042
PMCID: PMC3971593

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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