Article
Covariation in frequencies of substitution, deletion, transposition, and recombination during eutherian evolution.
Genome research - 1 Jan 2003
Hardison Ross C, Roskin Krishna M, Yang Shan, Diekhans Mark, Kent W James, Weber Ryan, Elnitski Laura, Li Jia, O'Connor Michael, Kolbe Diana, Schwartz Scott, Furey Terrence S, Whelan Simon, Goldman Nick, Smit Arian, Miller Webb, Chiaromonte Francesca, Haussler David
Abstract excerpt
Six measures of evolutionary change in the human genome were studied, three derived from the aligned human and mouse genomes in conjunction with the Mouse Genome Sequencing Consortium, consisting of (1) nucleotide substitution per fourfold degenerate site in coding regions, (2) nucleotide substitution per site in relics of transposable elements active only before the human-mouse speciation, and (3) the...
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