Article
HIP1: trafficking roles and regulation of tumorigenesis.
Trends in molecular medicine - 1 Apr 2004
Hyun Teresa S, Ross Theodora S
Abstract excerpt
During recent years, alterations in proteins of the endocytic pathway have been associated with tumors. Disrupted regulation of the endocytic pathway is a relatively unstudied mechanism of tumorigenesis, which can concomitantly disrupt several different signaling pathways to affect growth, differentiation and survival. Several endocytic proteins have been identified, either as part of tumor-associated...
Topics
- Alleles
- Biological Transport
- Cell Survival
- Cell Transformation, Neoplastic
- DNA-Binding Proteins
- Endocytosis
- Gene Expression Regulation, Neoplastic
- Humans
- Models, Biological
- Neoplasms
- Protein Structure, Tertiary
