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HIP1R acts as a tumor suppressor in gastric cancer by promoting cancer cell apoptosis and inhibiting migration and invasion through modulating Akt

16 Jun 2020

Abstract excerpt

BACKGROUND: Huntingtin-interacting protein 1-related (HIP1R) is a multi-domain gene that exerts many cellular functions including altering T cell-mediated cytotoxicity and controlling intracellular trafficking. However, its clinical significance and function in gastric cancer (GC) have not been described. METHODS: The expression levels of HIP1R were tested by the transcriptional and translational expression...

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PMID: 32548851
DOI: 10.1002/jcla.23425

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