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Article

Hip1-related mutant mice grow and develop normally but have accelerated spinal abnormalities and dwarfism in the absence of HIP1.

Molecular and cellular biology - 1 May 2004

Hyun Teresa S, Li Lina, Oravecz-Wilson Katherine I, Bradley Sarah V, Provot Melissa M, Munaco Anthony J, Mizukami Ikuko F, Sun Hanshi, Ross Theodora S

Abstract excerpt

In mice and humans, there are two known members of the Huntingtin interacting protein 1 (HIP1) family, HIP1 and HIP1-related (HIP1r). Based on structural and functional data, these proteins participate in the clathrin trafficking network. The inactivation of Hip1 in mice leads to spinal, hematopoietic, and testicular defects. To investigate the biological function of HIP1r, we generated a Hip1r mutant allele in...

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Identifiers

PMID: 15121852
DOI: 10.1128/MCB.24.10.4329-4340.2004
PMCID: PMC400480

Genes

HIP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Hip1-related mutant mice grow and develop normally but have accelerated spinal abnormalities and dwarfism in the absence of HIP1.PMID 15121852Read ↗

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