Alterations of the M6p/Igf2 receptor gene in hepatocellular carcinomas induced by N-nitrosodiethylamine and a choline-deficient L-amino acid-defined diet in rats.

doi:10.1002/mc.20010

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Article

Alterations of the M6p/Igf2 receptor gene in hepatocellular carcinomas induced by N-nitrosodiethylamine and a choline-deficient L-amino acid-defined diet in rats.

Molecular carcinogenesis - 1 Apr 2004

Tsujiuchi Toshifumi, Sasaki Yasutaka, Oka Yasuo, Kuniyasu Hiroki, Konishi Yoichi, Tsutsumi Masahiro

Abstract excerpt

To elucidate whether the M6p/Igf2 receptor (M6p/Igf2r) gene might be involved in exogenous and endogenous liver carcinogenesis, we investigated its alteration in hepatocellular carcinomas (HCCs) induced by N-nitrosodiethylamine (DEN) and by a choline-deficient L-amino acid-defined (CDAA) diet in...

Topics

Alkylating Agents
Animals
Carcinoma, Hepatocellular
Cell Cycle
Choline Deficiency
Codon
Colchicine
Diethylnitrosamine
Food Deprivation
Gout Suppressants
Hepatectomy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Liver Neoplasms, Experimental

Male

Mutation

Polymorphism, Single-Stranded Conformational

RNA, Neoplasm

Rats

Rats, Inbred F344

Source

Open in PubMed

Identifiers

PMID: 15057872
DOI: 10.1002/mc.20010

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-15057872-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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